The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail:
ncRNA Symmbol:ANRIL
ncRNA Category:lncRNA
Interaction Gene Symbol: KLF2
Death Pathway:apoptosis
Expression Direction of ncRNA:down
Species:Homo sapiens
Tissue:lung
PMID: 25504755
Detail Description:

In addition, taking advantage of loss-of-function experiments in NSCLC cells,we found that knockdown of ANRIL expression could impair cell proliferation and induce cell apoptosis both in vitro and vivo through silencing of KLF2 and P21 transcription. 

Select the ncRNA symbol and transcript of gene
lncRNA symbol :     Transcript of KLF2    
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting entry with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting entry with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.