Detail: | |
ncRNA Symmbol: | ANRIL |
---|---|
ncRNA Category: | lncRNA |
Interaction Gene Symbol: | KLF2 |
Death Pathway: | apoptosis |
Expression Direction of ncRNA: | down |
Species: | Homo sapiens |
Tissue: | lung |
PMID: | 25504755 |
Detail Description: | In addition, taking advantage of loss-of-function experiments in NSCLC cells,we found that knockdown of ANRIL expression could impair cell proliferation and induce cell apoptosis both in vitro and vivo through silencing of KLF2 and P21 transcription. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting entry with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting entry with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.