| Detail: | |
| ncRNA Symmbol: | miR-34a |
|---|---|
| ncRNA Category: | miRNA |
| Interaction Gene Symbol: | ATG4B |
| Death Pathway: | autophagy |
| Expression Direction of ncRNA: | down |
| Species: | Homo sapiens |
| Tissue: | chronic myeloid leukemia |
| PMID: | 24755409 |
| Detail Description: | Moreover, deregulated expression of ATG4B in CD34(+) CML cells inversely correlates with transcript levels of miR-34a, and ATG4B is shown to be a direct target of miR-34a. This study identifies ATG4B as a potential biomarker for predicting therapeutic response in treatment-na?ve CML stem/progenitor cells and uncovers ATG4B as a possible drug target in these cells. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting entry with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting entry with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.