The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail:
ncRNA Symmbol:miR-20a
ncRNA Category:miRNA
Interaction Gene Symbol: ATG9A
Death Pathway:autophagy
Expression Direction of ncRNA:down
Species:Homo sapiens
Tissue:osteoclast
PMID: 25485521
Detail Description:

Results of chromatin immunoprecipitation assay showed that HIF-1¦Á binds to miRNA-20a. From miRNA Q-PCR results, we confirmed that shRNA HIF-1¦Á knockdown significantly downregulated both autophagy (LC3, p62, Atg5, Atg12, Atg16l1, Atg7, Becn1, Atg9a) and osteoclast markers (Traf6, Nfatc1, Ctsk, cFos, Mmp9, Trap) in RAW264.7 cells.  

Select the ncRNA symbol and transcript of gene
Mature of miR-20a    Transcript of ATG9A    
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting entry with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting entry with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.