Detail: | |
ncRNA Symmbol: | miR-200c |
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ncRNA Category: | miRNA |
Interaction Gene Symbol: | TFAP2A |
Death Pathway: | apoptosis |
Expression Direction of ncRNA: | down |
Species: | Homo sapiens |
Tissue: | endometrial cancer |
PMID: | 22194984 |
Detail Description: | The transcription factor AP-2¦Á functions as a tumor suppressor by regulating various genes that are involved in cell proliferation and apoptosis. Luciferase assays and Western blot analysis demonstrated that the miR-200b/200c/429 family recognized the MRE in the 3' UTR of AP-2¦Á gene and negatively regulated the expression of endogenous AP-2¦Á proteins. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting entry with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting entry with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.