| Detail: | |
| ncRNA Symmbol: | miR-10b-5p |
|---|---|
| ncRNA Category: | miRNA |
| Interaction Gene Symbol: | E2F3 |
| Death Pathway: | apoptosis |
| Expression Direction of ncRNA: | down |
| Species: | Homo sapiens |
| Tissue: | myeloma |
| PMID: | 25330074 |
| Detail Description: | The effects of these miRNAs in modulating MM cell apoptosis was also investigated; re-expression of miR-152, -10b-5p and miR-34c-3p mimics induced cleavage of PARP- and caspase-9 and -3, compared to normal control-transfected cells.E2F transcription factor 3 (E2F3), predicted target of both miR-152 and miR-10b-5p were examined in MM cells,In addition, E2F3 were significantly increased after miR-10b-5p mimic transfection |
The 'First Node' or 'Second Node' option represents the sub-network of interacting entry with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting entry with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.