The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail:
ncRNA Symmbol:miR-518b
ncRNA Category:miRNA
Interaction Gene Symbol: RAP1B
Death Pathway:apoptosis
Expression Direction of ncRNA:up
Species:Homo sapiens
Tissue:esophageal squamous cell carcinoma cells
PMID: 22958893
Detail Description:

miR-518b suppressed the proliferation by inducing apoptosis and repressed the invasion in ESCC cells, but had no effect on the cell cycle. Furthermore, Rap1b was revealed to be directly regulated by miR-518b.  

Select the ncRNA symbol and transcript of gene
Mature of miR-518b    Transcript of RAP1B    
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting entry with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting entry with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.