Detail: | |
ncRNA Symmbol: | miR-30 |
---|---|
ncRNA Category: | miRNA |
Interaction Gene Symbol: | TP53 |
Death Pathway: | apoptosis |
Expression Direction of ncRNA: | down |
Species: | Homo sapiens |
Tissue: | |
PMID: | 25137026 |
Detail Description: | Tp53 is a validated target of miR-30 whose levels fall under ischemic conditions.The concomitant decrease in p53 protein content reduces Bax expression and limits mitochondrial membrane depolarization resulting in preserved mitochondrial function and decreased apoptosis and necrosis extent in the area at risk (AAR). |
The 'First Node' or 'Second Node' option represents the sub-network of interacting entry with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting entry with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.