Detail: | |
ncRNA Symmbol: | miR-17 |
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ncRNA Category: | miRNA |
Interaction Gene Symbol: | ZBTB4 |
Death Pathway: | apoptosis |
Expression Direction of ncRNA: | down |
Species: | Homo sapiens |
Tissue: | chronic lymphocytic leukemia cells |
PMID: | 22343732 |
Detail Description: | The enforced expression of miR-17, a major member from this family, reduced the expression of the tumor suppressor genes E2F5, TP53INP1, TRIM8 and ZBTB4, and protected cells from serum-free-induced apoptosis (P ¨P 0.05). |
The 'First Node' or 'Second Node' option represents the sub-network of interacting entry with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting entry with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.