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Detail Information


Basic information:


Untranslated mRNA: Sponge mRNA

Related IDs cncRNA ID CNC_M_002049
Name ZNF460
Gene ID 10794
Location Coordinate(Strand) 19:57280051-57294069(+)
Locus Sequence
Organism Homo sapiens

Evidence support:

  
In vivo/vitro assay In vitro assay
Low-throughput method Transfection assay;Western blotting;qRT-PCR;Luciferase assay;RNA-immunoprecipitation
High-throughput method /
Tissue/Cell DU145 cell;HCT116 cell;DICERE cell
Description of experimental evidence The mRNA was detected by transfection assay, western blotting, qRT-PCR, luciferase assay,RNA-immunoprecipitation in DU145 cell, which can act as a miR-mediated PTEN regulators.

Orthologues:

  
Chimpanzee ENSPTRG00000011548  
Mouse /
Drosophila /
Zebrafish /

References:

  
PMID 22000013
Description By a combined computational and experimental approach, we identified and validated endogenous protein-coding transcripts that regulate PTEN, antagonize PI3K/AKT signaling, and possess growth- and tumor-suppressive properties.

Related Subcelluar Localization:

  
Subcelluar Localization RLID Link to RNALocate
chromatin RLID00054847 Link to RNALocate
cytosol RLID00054848 Link to RNALocate
cytosol RLID00054849 Link to RNALocate
nucleolus RLID00054850 Link to RNALocate
nucleoplasm RLID00054851 Link to RNALocate
exosome RLID00054852 Link to RNALocate
Nucleus RLID00001583 Link to RNALocate

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).