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Detail Information


Basic information:


Untranslated mRNA: Sponge mRNA

Related IDs cncRNA ID CNC_M_001921
Name ZEB2
Gene ID 9839
Location Coordinate(Strand) 2:144364364-144521057(-)
Locus Sequence
Organism Homo sapiens

Evidence support:

  
In vivo/vitro assay In vitro assay and in vivo assay (Mouse)
Low-throughput method Transfection assay;Western blotting;qRT-PCR;Luciferase assay;siRNA;Proliferation assay
High-throughput method /
Tissue/Cell A375 cell;WM35 cell;451Lu cell;WM278 cell
Description of experimental evidence The mRNA was detected by transfection assay, western blotting, qRT-PCR, luciferase assay, siRNA and proliferation assay in A375 cell, WM35 cell, 451Lu cell and WM278 cell, which can act as a decoy for Pten-targeting microRNAs in melanoma

Orthologues:

  
Chimpanzee ENSPTRG00000012513  
Mouse ENSMUSG00000026872  
Drosophila /
Zebrafish ENSDARG00000078416  

References:

  
PMID 22000016
Description We report the discovery of significant enrichment of putative PTEN ceRNAs among genes whose loss accelerates tumorigenesis following sleeping beauty insertional mutagenesis in a mouse model of melanoma.

Related Subcelluar Localization:

  
Subcelluar Localization RLID Link to RNALocate
Cytosol RLID00026595 Link to RNALocate
chromatin RLID00116712 Link to RNALocate
cytosol RLID00116713 Link to RNALocate
nucleolus RLID00116714 Link to RNALocate
nucleoplasm RLID00116715 Link to RNALocate
nucleus RLID00116716 Link to RNALocate
nucleus RLID00116717 Link to RNALocate
nucleus RLID00116718 Link to RNALocate
exosome RLID00116719 Link to RNALocate

Related Diseases:

  
OMIM Phenotype Phenotype MIM number Link to OMIM
Mowat-Wilson syndrome OMIM:235730 Link to OMIM

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).