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Detail Information


Basic information:


Untranslated mRNA: Sponge mRNA

Related IDs cncRNA ID CNC_M_002040
Name VCAN
Gene ID 1462
Location Coordinate(Strand) 5:83471618-83582303(+)
Locus Sequence
Organism Homo sapiens

Evidence support:

  
In vivo/vitro assay In vitro assay and in vivo assay (Mouse)
Low-throughput method Transfection assay;Western blotting;qRT-PCR;Luciferase assay;siRNA;Cell proliferation assay;Cell survival assay;Colony formation in soft agarose gel;Cell migration assay;Cell invasion assay
High-throughput method /
Tissue/Cell HepG2 cell
Description of experimental evidence The mRNA was detected by transfection assay, western blotting, qRT-PCR and luciferase assay in HepG2 cell, which can induce the development of hepatocellular carcinoma by regulating miRNA activity.

Orthologues:

  
Chimpanzee ENSPTRG00000017055  
Mouse ENSMUSG00000021614  
Drosophila /
Zebrafish ENSDARG00000103515   ENSDARG00000009401  

References:

  
PMID 23180826
Description Versican 3'-untranslated Region (3'-UTR) functions as a ceRNA in inducing the development of hepatocellular carcinoma by regulating miRNA activity. Moreover, the ceRNA function of FN1 and CD34 were showd in Figure 5

Related Subcelluar Localization:

  
Subcelluar Localization RLID Link to RNALocate
exosome RLID00059991 Link to RNALocate
Ribosome RLID00003695 Link to RNALocate
Endoplasmic reticulum RLID00003696 Link to RNALocate

Related Diseases:

  
OMIM Phenotype Phenotype MIM number Link to OMIM
Wagner syndrome 1 OMIM:143200 Link to OMIM

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).