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Detail Information


Basic information:


Untranslated mRNA: Sponge mRNA

Related IDs cncRNA ID CNC_M_002040
Name VCAN
Gene ID 1462
Location Coordinate(Strand) 5:83471618-83582303(+)
Locus Sequence
Organism Homo sapiens

Evidence support:

  
In vivo/vitro assay In vitro assay and in vivo assay (Mouse)
Low-throughput method Transfection assay;Western blotting;qRT-PCR;Dual luciferase reporter assay;Tumor formation assay;Immunohistochemistry
High-throughput method /
Tissue/Cell 4T1 cell
Description of experimental evidence The mRNA was detected by transfection assay, western blotting, qRT-PCR, dual luciferase reporter assay, tumor formation assay, immunohistochemistry in 4T1 cell, which can bind miR-144, miR-199a-3p, acting as a decoy for Vcan-targeting microRNAs.

Orthologues:

  
Chimpanzee ENSPTRG00000017055  
Mouse ENSMUSG00000021614  
Drosophila /
Zebrafish ENSDARG00000103515   ENSDARG00000009401  

References:

  
PMID 21049042
Description Our results demonstrated that a 3'UTR fragment can be used to modulate miRNA functions. Our study also suggests that miRNAs in the cancer cells are more susceptible to degradation, due to its interaction with a non-coding 3'UTR.

Related Subcelluar Localization:

  
Subcelluar Localization RLID Link to RNALocate
exosome RLID00059991 Link to RNALocate
Ribosome RLID00003695 Link to RNALocate
Endoplasmic reticulum RLID00003696 Link to RNALocate

Related Diseases:

  
OMIM Phenotype Phenotype MIM number Link to OMIM
Wagner syndrome 1 OMIM:143200 Link to OMIM

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).