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Detail Information
Basic information:
Untranslated mRNA: Sponge mRNA
| Related IDs | cncRNA ID | CNC_M_002029 | |
|---|---|---|---|
| Name | TNRC6B | ||
| Gene ID | 23112 | ||
| Location | Coordinate(Strand) | 22:40044817-40335808(+) | |
| Locus Sequence | |||
| Organism | Homo sapiens | ||
Evidence support:
| In vivo/vitro assay | In vitro assay and in vivo assay (Mouse) | |
|---|---|---|
| Low-throughput method | Transfection assay;Western blotting;qRT-PCR;Luciferase assay;siRNA;Proliferation assay | |
| High-throughput method | / | |
| Tissue/Cell | A375 cell;WM35 cell;451Lu cell;WM278 cell | |
| Description of experimental evidence | The mRNA was detected by transfection assay, western blotting, qRT-PCR, luciferase assay, siRNA and proliferation assay in A375 cell, WM35 cell, 451Lu cell and WM278 cell, which can act as a decoy for Pten-targeting microRNAs in melanoma | |
Orthologues:
| Chimpanzee | ENSPTRG00000047826 |
|---|---|
| Mouse | ENSMUSG00000047888 |
| Drosophila | / |
| Zebrafish | ENSDARG00000074161 ENSDARG00000079723 ENSDARG00000076389 |
References:
| PMID | 22000016 |
|---|---|
| Description | We report the discovery of significant enrichment of putative PTEN ceRNAs among genes whose loss accelerates tumorigenesis following sleeping beauty insertional mutagenesis in a mouse model of melanoma. |
Related Subcelluar Localization:
| Subcelluar Localization | RLID | Link to RNALocate |
|---|---|---|
| chromatin | RLID00066213 | Link to RNALocate |
| cytosol | RLID00066214 | Link to RNALocate |
| cytosol | RLID00066215 | Link to RNALocate |
| cytosol | RLID00066216 | Link to RNALocate |
| membrane | RLID00066217 | Link to RNALocate |
| nucleolus | RLID00066218 | Link to RNALocate |
| nucleoplasm | RLID00066219 | Link to RNALocate |
| nucleus | RLID00066220 | Link to RNALocate |
| nucleus | RLID00066221 | Link to RNALocate |
| nucleus | RLID00066222 | Link to RNALocate |
| exosome | RLID00066223 | Link to RNALocate |
| Cytosol | RLID00006894 | Link to RNALocate |
| Nucleus | RLID00006895 | Link to RNALocate |
| Ribosome | RLID00006896 | Link to RNALocate |
Related Interactions:
Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).