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Detail Information


Basic information:


Untranslated mRNA: Sponge mRNA

Related IDs cncRNA ID CNC_M_002027
Name TNRC6A
Gene ID 27327
Location Coordinate(Strand) 16:24610209-24827632(+)
Locus Sequence
Organism Homo sapiens

Evidence support:

  
In vivo/vitro assay In vitro assay and in vivo assay (Mouse)
Low-throughput method Transfection assay;Western blotting;qRT-PCR;Luciferase assay;siRNA;Proliferation assay
High-throughput method /
Tissue/Cell A375 cell;WM35 cell;451Lu cell;WM278 cell
Description of experimental evidence The mRNA was detected by transfection assay, western blotting, qRT-PCR, luciferase assay, siRNA and proliferation assay in A375 cell, WM35 cell, 451Lu cell and WM278 cell, which can act as a decoy for Pten-targeting microRNAs in melanoma

Orthologues:

  
Chimpanzee ENSPTRG00000007898  
Mouse ENSMUSG00000052707  
Drosophila /
Zebrafish ENSDARG00000079688  

References:

  
PMID 22000016
Description We report the discovery of significant enrichment of putative PTEN ceRNAs among genes whose loss accelerates tumorigenesis following sleeping beauty insertional mutagenesis in a mouse model of melanoma.

Related Subcelluar Localization:

  
Subcelluar Localization RLID Link to RNALocate
Nucleus RLID00039123 Link to RNALocate
chromatin RLID00072295 Link to RNALocate
cytosol RLID00072296 Link to RNALocate
cytosol RLID00072297 Link to RNALocate
insoluble cytoplasm RLID00072298 Link to RNALocate
membrane RLID00072299 Link to RNALocate
membrane RLID00072300 Link to RNALocate
nucleoplasm RLID00072301 Link to RNALocate
nucleus RLID00072302 Link to RNALocate
nucleus RLID00072303 Link to RNALocate
nucleus RLID00072304 Link to RNALocate
exosome RLID00072305 Link to RNALocate
Nucleus RLID00009134 Link to RNALocate

Related Diseases:

  
OMIM Phenotype Phenotype MIM number Link to OMIM
Epilepsy, familial adult myoclonic, 6 OMIM:618074 Link to OMIM

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).