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Detail Information


Basic information:


Untranslated mRNA: Sponge mRNA

Related IDs cncRNA ID CNC_M_001822
Name SENP1
Gene ID 29843
Location Coordinate(Strand) 12:48042897-48106079(-)
Locus Sequence
Organism Homo sapiens

Evidence support:

  
In vivo/vitro assay In vitro assay and in vivo assay (Mouse)
Low-throughput method Transfection assay;Western blotting;qRT-PCR;Luciferase assay;RNA immune co-precipitation assay
High-throughput method /
Tissue/Cell HUVEC cell
Description of experimental evidence The mRNA was detected by transfection assay, western blotting, qRT-PCR, luciferase assay and RNA immune co-precipitation assay in HUVEC cell, which can act as a ceRNA for TGFBR2 and thus activates TGFBR2/Smad signaling responsible for LPS-induced sepsis

Orthologues:

  
Chimpanzee ENSPTRG00000004872  
Mouse ENSMUSG00000033075  
Drosophila /
Zebrafish ENSDARG00000078574  

References:

  
PMID 30797150
Description SUMO protease SENP1 acts as a ceRNA for TGFBR2 and thus activates TGFBR2/Smad signaling responsible for LPS-induced sepsis.

Related Subcelluar Localization:

  
Subcelluar Localization RLID Link to RNALocate
cytosol RLID00074633 Link to RNALocate
cytosol RLID00074634 Link to RNALocate
membrane RLID00074635 Link to RNALocate
nucleoplasm RLID00074636 Link to RNALocate
nucleus RLID00074637 Link to RNALocate
nucleus RLID00074638 Link to RNALocate
exosome RLID00074639 Link to RNALocate
Cytosol RLID00009861 Link to RNALocate

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).