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Detail Information


Basic information:


Untranslated mRNA: Sponge mRNA

Related IDs cncRNA ID CNC_M_001999
Name Pten
Gene ID 19211
Location Coordinate(Strand) 19:32757497-32826160(+)
Locus Sequence
Organism Mus musculus

Evidence support:

  
In vivo/vitro assay In vitro assay and in vivo assay (Mouse)
Low-throughput method Transfection assay;Western blotting;qRT-PCR;Dual luciferase reporter assay;Tumor formation assay;Immunohistochemistry
High-throughput method /
Tissue/Cell 4T1 cell
Description of experimental evidence The mRNA was detected by transfection assay, western blotting, qRT-PCR, dual luciferase reporter assay, tumor formation assay, immunohistochemistry in 4T1 cell, which can bind miR-136, miR-144, acting as a decoy for Vcan-targeting microRNAs.

Orthologues:

  
Human ENSG00000171862  
Chimpanzee ENSPTRG00000002719  
Drosophila FBgn0026379  
Zebrafish ENSDARG00000071018   ENSDARG00000056623  

References:

  
PMID 21049042
Description Our results demonstrated that a 3'UTR fragment can be used to modulate miRNA functions. Our study also suggests that miRNAs in the cancer cells are more susceptible to degradation, due to its interaction with a non-coding 3'UTR.

Related Subcelluar Localization:

  
Subcelluar Localization RLID Link to RNALocate
Cytoplasm RLID00005017 Link to RNALocate

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).