Basic information:

Untranslated mRNA: Sponge mRNA

Related IDs	cncRNA ID	CNC_M_001998
	Name	PTCH1
	Gene ID	5727
Location	Coordinate(Strand)	9:95442980-95517057(-)
Locus Sequence
Organism	Homo sapiens

Evidence support:

  

In vivo/vitro assay	In vitro assay
Low-throughput method	Transfection assay;Western blotting;qRT-PCR;Luciferase assay;Transwell migration and invasion assay;Overexpression;Adhesion assay
High-throughput method	/
Tissue/Cell	NCI-H1299 cell;A549 cell
Description of experimental evidence	The mRNA was detected by transfection assay, western blotting, qRT-PCR and luciferase assay in NCI-H1299 cell and A549 cell, which promote Cell migration assay and invasion by activating miR-101-3p/SLC39A6 axis in non-small cell lung cancer.

Orthologues:

  

Chimpanzee	ENSPTRG00000046951
Mouse	ENSMUSG00000021466
Drosophila	FBgn0262867   FBgn0003892   FBgn0029088
Zebrafish	ENSDARG00000095859   ENSDARG00000016404

References:

  

PMID	29435142
Description	By combining weighted correlation network analysis (WGCNA) analysis and experimental validation, we reported PTCH1-3'UTR acted as a sponge to absorb miR-101-3p and promoted SLC39A6 expression.

Related Subcelluar Localization:

  

Subcelluar Localization	RLID	Link to RNALocate
chromatin	RLID00093200	Link to RNALocate
membrane	RLID00093201	Link to RNALocate
nucleolus	RLID00093202	Link to RNALocate
nucleoplasm	RLID00093203	Link to RNALocate
nucleus	RLID00093204	Link to RNALocate
nucleus	RLID00093205	Link to RNALocate
nucleus	RLID00093206	Link to RNALocate
exosome	RLID00093207	Link to RNALocate
Endoplasmic reticulum	RLID00017288	Link to RNALocate

Related Diseases:

  

OMIM Phenotype	Phenotype MIM number	Link to OMIM
Basal cell nevus syndrome	OMIM:109400	Link to OMIM
Holoprosencephaly 7	OMIM:610828	Link to OMIM
Basal cell carcinoma, somatic	OMIM:605462	Link to OMIM

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).