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Detail Information


Basic information:


Untranslated mRNA: Sponge mRNA

Related IDs cncRNA ID CNC_M_001994
Name PIK3C2A
Gene ID 5286
Location Coordinate(Strand) 11:17077730-17207983(-)
Locus Sequence
Organism Homo sapiens

Evidence support:

  
In vivo/vitro assay In vitro assay and in vivo assay (Mouse)
Low-throughput method Transfection assay;Western blotting;qRT-PCR;Luciferase assay;RIP assay;MTT assay;Transwell migration and invasion assay;Immunohistochemistry;Adhesion assay
High-throughput method /
Tissue/Cell Hepatocellular carcinoma sample;QGY-7703 cell;SMMC-7721 cell;HL-7702 cell
Description of experimental evidence The mRNA was detected by transfection assay, western blotting, qRT-PCR, luciferase assay, RIP assay, colony formation assay and transwell migration and invasion assay in HCC cell, hepatocellular carcinoma sample, QGY-7703 cell, SMMC-7721 cell and HL-7702 cell, which can enhance malignancy of hepatocellular carcinoma cells by sponging miR-124,acting as a decoy for CD151-targeting microRNAs

Orthologues:

  
Chimpanzee ENSPTRG00000003399  
Mouse ENSMUSG00000030660  
Drosophila FBgn0015279   FBgn0015278  
Zebrafish ENSDARG00000060841  

References:

  
PMID 27270320
Description PIK3C2A mRNA functions as a miR-124 sponge to facilitate CD151 expression and enhance malignancy of hepatocellular carcinoma cells.

Related Subcelluar Localization:

  
Subcelluar Localization RLID Link to RNALocate
chromatin RLID00085720 Link to RNALocate
cytosol RLID00085721 Link to RNALocate
membrane RLID00085722 Link to RNALocate
nucleolus RLID00085723 Link to RNALocate
nucleoplasm RLID00085724 Link to RNALocate
nucleus RLID00085725 Link to RNALocate
exosome RLID00085726 Link to RNALocate
Nucleus RLID00015106 Link to RNALocate
Ribosome RLID00015107 Link to RNALocate
Cytosol RLID00015108 Link to RNALocate

Related Diseases:

  
OMIM Phenotype Phenotype MIM number Link to OMIM
Oculoskeletodental syndrome OMIM:618440 Link to OMIM

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).