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Detail Information


Basic information:


Untranslated mRNA: Sponge mRNA

Related IDs cncRNA ID CNC_M_001983
Name Mbnl1
Gene ID 56758
Location Coordinate(Strand) 3:60472830-60629750(+)
Locus Sequence
Organism Mus musculus

Evidence support:

  
In vivo/vitro assay In vitro assay and in vivo assay (Mouse)
Low-throughput method Transfection assay;Western blotting;qRT-PCR;Luciferase assay;siRNA;Proliferation assay
High-throughput method /
Tissue/Cell A375 cell;WM35 cell;451Lu cell;WM278 cell
Description of experimental evidence The mRNA was detected by transfection assay, western blotting, qRT-PCR, luciferase assay, siRNA and proliferation assay in A375 cell, WM35 cell, 451Lu cell and WM278 cell, which can act as a decoy for Pten-targeting microRNAs in melanoma

Orthologues:

  
Human ENSG00000152601  
Chimpanzee ENSPTRG00000015542  
Drosophila FBgn0265487  
Zebrafish ENSDARG00000052978  

References:

  
PMID 22000016
Description We report the discovery of significant enrichment of putative PTEN ceRNAs among genes whose loss accelerates tumorigenesis following sleeping beauty insertional mutagenesis in a mouse model of melanoma.

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).