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Detail Information
Basic information:
Untranslated mRNA: Sponge mRNA
| Related IDs | cncRNA ID | CNC_M_001971 | |
|---|---|---|---|
| Name | Hmga2 | ||
| Gene ID | 15364 | ||
| Location | Coordinate(Strand) | 10:120361275-120476469(-) | |
| Locus Sequence | |||
| Organism | Mus musculus | ||
Evidence support:
| In vivo/vitro assay | In vitro assay and in vivo assay (Mouse) | |
|---|---|---|
| Low-throughput method | Transfection assay;Western blotting;qRT-PCR;Luciferase assay;BrdU analysis,siRNA/miRNA transfection;polyHEMA plating analysis;Histopathological analysis | |
| High-throughput method | / | |
| Tissue/Cell | 368T1 cell;482N1 cell;HEK293;NCI-H1299 cell;SK-MES-1 cell | |
| Description of experimental evidence | The mRNA was detected by transfection assay, western blotting, qRT-PCR, luciferase assay in 368T1 cell and 482N1 cell, which can bind let-7, acting as a decoy for Tgfb3-targeting microRNAs. | |
Orthologues:
| Human | / |
|---|---|
| Chimpanzee | / |
| Drosophila | / |
| Zebrafish | ENSDARG00000069912 |
References:
| PMID | 24305048 |
|---|---|
| Description | Here we show that Hmga2 promotes lung cancer progression in mouse and human cells by operating as a competing endogenous RNA (ceRNA) for the let-7 microRNA (miRNA) family. |
Related Interactions:
Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).