Basic information:

Untranslated mRNA: Sponge mRNA

Related IDs	cncRNA ID	CNC_M_001616
	Name	HMGA2
	Gene ID	8091
Location	Coordinate(Strand)	12:65824131-65966295(+)
Locus Sequence
Organism	Homo sapiens

Evidence support:

  

In vivo/vitro assay	In vitro assay and in vivo assay (Mouse)
Low-throughput method	Transfection assay;Western blotting;qRT-PCR;Luciferase assay;BrdU analysis,siRNA/miRNA transfection;polyHEMA plating analysis;Histopathological analysis
High-throughput method	/
Tissue/Cell	368T1 cell;482N1 cell;HEK293;NCI-H1299 cell;SK-MES-1 cell
Description of experimental evidence	The mRNA was detected by transfection assay, western blotting, qRT-PCR, luciferase assay in 368T1 cell and 482N1 cell, which can bind let-7a, let-7b, let-7c, let-7e, let-7i, acting as a decoy for TGFBR3-targeting microRNAs.

Orthologues:

  

Chimpanzee	ENSPTRG00000005184
Mouse	ENSMUSG00000108981
Drosophila	/
Zebrafish	ENSDARG00000033616   ENSDARG00000058978

References:

  

PMID	24305048
Description	Here we show that Hmga2 promotes lung cancer progression in mouse and human cells by operating as a competing endogenous RNA (ceRNA) for the let-7 microRNA (miRNA) family.

Related Subcelluar Localization:

  

Subcelluar Localization	RLID	Link to RNALocate
Nucleus	RLID00040700	Link to RNALocate
Cytoplasm	RLID00040701	Link to RNALocate
cytosol	RLID00106746	Link to RNALocate
insoluble cytoplasm	RLID00106747	Link to RNALocate
nucleus	RLID00106748	Link to RNALocate
exosome	RLID00106749	Link to RNALocate
Cytosol	RLID00022994	Link to RNALocate

Related Diseases:

  

OMIM Phenotype	Phenotype MIM number	Link to OMIM
Silver-Russell syndrome 5	OMIM:618908	Link to OMIM

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).