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Detail Information
Basic information:
Untranslated mRNA: Sponge mRNA
| Related IDs | cncRNA ID | CNC_M_001966 | |
|---|---|---|---|
| Name | HIF1A | ||
| Gene ID | 3091 | ||
| Location | Coordinate(Strand) | 14:61695513-61748259(+) | |
| Locus Sequence | |||
| Organism | Homo sapiens | ||
Evidence support:
| In vivo/vitro assay | In vitro assay and in vivo assay (Mouse) | |
|---|---|---|
| Low-throughput method | Transfection and exposing cells to hypoxia;Western blotting;qRT-PCR;Luciferase assay;Intraocular injection of miRNA mimic;Immunohistochemistry | |
| High-throughput method | / | |
| Tissue/Cell | ARPE-19 cell;Retinal pigment epithelium cell | |
| Description of experimental evidence | The mRNA was detected by transfection and exposing cells to hypoxia, western blotting, qRT-PCR and luciferase assay in ARPE-19 cell and retinal pigment epithelium (RPE) cell, which can act as a decoy for VEGF-targeting microRNAs | |
Orthologues:
| Chimpanzee | ENSPTRG00000006419 |
|---|---|
| Mouse | ENSMUSG00000021109 |
| Drosophila | FBgn0262139 FBgn0266411 |
| Zebrafish | ENSDARG00000034293 |
References:
| PMID | 24018047 |
|---|---|
| Description | MicroRNA-dependent cross-talk between VEGF and HIF1A in the Diabetic Retina. |
Related Subcelluar Localization:
| Subcelluar Localization | RLID | Link to RNALocate |
|---|---|---|
| chromatin | RLID00075362 | Link to RNALocate |
| cytosol | RLID00075363 | Link to RNALocate |
| cytosol | RLID00075364 | Link to RNALocate |
| cytosol | RLID00075365 | Link to RNALocate |
| insoluble cytoplasm | RLID00075366 | Link to RNALocate |
| nucleoplasm | RLID00075367 | Link to RNALocate |
| nucleus | RLID00075368 | Link to RNALocate |
| nucleus | RLID00075369 | Link to RNALocate |
| exosome | RLID00075370 | Link to RNALocate |
| Cytosol | RLID00010103 | Link to RNALocate |
| Nucleus | RLID00010104 | Link to RNALocate |
| Ribosome | RLID00010105 | Link to RNALocate |
| Endoplasmic reticulum | RLID00010106 | Link to RNALocate |
| Ribosome | RLID00010107 | Link to RNALocate |
Related Interactions:
Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).