Basic information:

Untranslated mRNA: Sponge mRNA

Related IDs	cncRNA ID	CNC_M_001946
	Name	CXCR4
	Gene ID	7852
Location	Coordinate(Strand)	2:136114349-136118149(-)
Locus Sequence
Organism	Homo sapiens

Evidence support:

  

In vivo/vitro assay	In vitro assay
Low-throughput method	Transfection assay;Western blotting;qRT-PCR;Luciferase assay;Immunofluorescence assay;Invasion assay;Wound healing assay;MTT assay;Adhesion assay;Transwell assay
High-throughput method	/
Tissue/Cell	MCF-7 cell
Description of experimental evidence	The mRNA was detected by transfection assay, western blotting, qRT-PCR, dual luciferase reporter assay, lentiviral infection in MCF-7 cell, which can promote metastasis, proliferation and survival of MCF-7 cells by binding miR-146a.

Orthologues:

  

Chimpanzee	ENSPTRG00000012501
Mouse	ENSMUSG00000045382
Drosophila	/
Zebrafish	ENSDARG00000041959   ENSDARG00000057633

References:

  

PMID	26095299
Description	CXCR4 3'UTR functions as a ceRNA in promoting metastasis, proliferation and survival of MCF-7 cells by regulating miR-146a activity.

Related Subcelluar Localization:

  

Subcelluar Localization	RLID	Link to RNALocate
nucleus	RLID00103839	Link to RNALocate
exosome	RLID00103840	Link to RNALocate
Ribosome	RLID00022209	Link to RNALocate
Endoplasmic reticulum	RLID00022210	Link to RNALocate

Related Diseases:

  

OMIM Phenotype	Phenotype MIM number	Link to OMIM
WHIM syndrome	OMIM:193670	Link to OMIM

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).