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Detail Information


Basic information:


Untranslated mRNA: Sponge mRNA

Related IDs cncRNA ID CNC_M_001942
Name Cnot6l
Gene ID 231464
Location Coordinate(Strand) 5:96070333-96164171(-)
Locus Sequence
Organism Mus musculus

Evidence support:

  
In vivo/vitro assay In vitro assay
Low-throughput method Transfection assay;Western blotting;qRT-PCR;Luciferase assay;RNA-immunoprecipitation
High-throughput method /
Tissue/Cell DU144 cell;Glioblastoma sample
Description of experimental evidence The mRNA was detected by transfection assay, western blotting, qRT-PCR, luciferase assay,RNA-immunoprecipitation in DU144 cell, which can bind miR-17, miR-19a, miR-20a, miR-20b, miR-26b, miR-106a, miR-106b, acting as a decoy for Pten-targeting microRNAs.

Orthologues:

  
Human ENSG00000138767  
Chimpanzee ENSPTRG00000045291   ENSPTRG00000016198  
Drosophila FBgn0016762   FBgn0011725  
Zebrafish ENSDARG00000054597  

References:

  
PMID 22000013
Description By a combined computational and experimental approach, we identified and validated endogenous protein-coding transcripts that regulate PTEN, antagonize PI3K/AKT signaling, and possess growth- and tumor-suppressive properties.

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).