Basic information:

Untranslated mRNA: Sponge mRNA

Related IDs	cncRNA ID	CNC_M_001939
	Name	CDC42
	Gene ID	998
Location	Coordinate(Strand)	1:22025511-22101360(+)
Locus Sequence
Organism	Homo sapiens

Evidence support:

  

In vivo/vitro assay	In vitro assay
Low-throughput method	Transfection assay;Western blotting;qRT-PCR;Luciferase activity assay;Colony and Tumor formation assay;Immunohistochemistry
High-throughput method	/
Tissue/Cell	MT-1 cell
Description of experimental evidence	The mRNA was detected by transfection assay, western blotting, qRT-PCR, luciferase activity assay, colony and tumor formation assay, immunohistochemistry in MT-1 cell, which can bind miR-216a, miR-330, miR-608, acting as a decoy for CD44-targeting microRNAs.

Orthologues:

  

Chimpanzee	ENSPTRG00000051031
Mouse	ENSMUSG00000006699
Drosophila	/
Zebrafish	ENSDARG00000044573

References:

  

PMID	21149267
Description	These results are due to the interaction of the CD44 3'-UTR with multiple miRNAs. Computational algorithms have predicted three miRNAs, miR-216a, miR-330 and miR-608, can bind to both the CD44 and CDC42 3'-UTRs. This was confirmed with luciferase assays, western blotting and immunohistochemical staining and correlated with a series of siRNA assays.

Related Subcelluar Localization:

  

Subcelluar Localization	RLID	Link to RNALocate
Ribosome	RLID00026797	Link to RNALocate
Ribosome	RLID00026798	Link to RNALocate
Nucleus	RLID00026799	Link to RNALocate
Cytoplasm	RLID00026800	Link to RNALocate
Cytosol	RLID00026801	Link to RNALocate
chromatin	RLID00117433	Link to RNALocate
cytosol	RLID00117434	Link to RNALocate
cytosol	RLID00117435	Link to RNALocate
nucleolus	RLID00117436	Link to RNALocate
nucleoplasm	RLID00117437	Link to RNALocate
nucleus	RLID00117438	Link to RNALocate
exosome	RLID00117439	Link to RNALocate

Related Diseases:

  

OMIM Phenotype	Phenotype MIM number	Link to OMIM
Takenouchi-Kosaki syndrome	OMIM:616737	Link to OMIM

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).