Basic information:

Untranslated mRNA: Sponge mRNA

Related IDs	cncRNA ID	CNC_M_001938
	Name	CD44
	Gene ID	960
Location	Coordinate(Strand)	11:35138870-35232402(+)
Locus Sequence
Organism	Homo sapiens

Evidence support:

  

In vivo/vitro assay	In vitro assay and in vivo assay (Mouse)
Low-throughput method	Transfection assay;Western blotting;qRT-PCR;Luciferase assay;siRNA;Cell detachment;Cell migration assay;Cell invasion assay;Tumor formation assay;Immunohistochemistry
High-throughput method	/
Tissue/Cell	MDA-MB-231 cell
Description of experimental evidence	The mRNA was detected by transfection assay, western blotting, qRT-PCR, luciferase assay and siRNA in MDA-MB-231 cell, which can induce metastasis by regulating extracellular matrix functions

Orthologues:

  

Chimpanzee	ENSPTRG00000003501
Mouse	ENSMUSG00000005087
Drosophila	/
Zebrafish	/

References:

  

PMID	22637644
Description	Protein analysis demonstrated that expression of CD44, Col1A1 and FN1 were synergistically upregulated in vitro and in vivo upon transfection of the CD44 3' UTR. The non-coding 3' UTR of CD44 interacts with multiple miRNAs that target extracellular matrix properties and thus can be used to antagonize miRNA activities.

Related Subcelluar Localization:

  

Subcelluar Localization	RLID	Link to RNALocate
Nucleus	RLID00026309	Link to RNALocate
Endoplasmic reticulum	RLID00026310	Link to RNALocate
Nucleus	RLID00041165	Link to RNALocate
nucleus	RLID00115522	Link to RNALocate
exosome	RLID00115523	Link to RNALocate

Related Diseases:

  

OMIM Phenotype	Phenotype MIM number	Link to OMIM
Blood group, Indian system	OMIM:609027	Link to OMIM

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).