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Detail Information


Basic information:


Untranslated mRNA: Sponge mRNA

Related IDs cncRNA ID CNC_M_001934
Name CCR2
Gene ID 729230
Location Coordinate(Strand) 3:46353734-46360928(+)
Locus Sequence
Organism Homo sapiens

Evidence support:

  
In vivo/vitro assay In vitro assay and in vivo assay (Mouse)
Low-throughput method Transfection assay;Western blotting;qRT-PCR;Luciferase assay;Transwell migration and invasion assay;Wound healing assay;Adhesion assay;RNA-binding protein immunoprecipitation assay;Immunofluorescence assay;RhoA GTPase assay
High-throughput method /
Tissue/Cell MDA-MB-231 cell;MCF-7 cell
Description of experimental evidence The mRNA was detected by transfection assay, western blotting, qRT-PCR and luciferase assay in MDA-MB-231 cell and MCF-7 cell, which function as a competing endogenous RNA to inhibit breast cancer metastasis by sponging miR-125b.

Orthologues:

  
Chimpanzee ENSPTRG00000014847  
Mouse ENSMUSG00000049103  
Drosophila /
Zebrafish /

References:

  
PMID 28818997
Description The CCR2 3'UTR modulated the expression of the RhoGAP protein STARD13 via acting as a STARD13 ceRNA in a microRNA-dependent and protein coding-independent manner.

Related Subcelluar Localization:

  
Subcelluar Localization RLID Link to RNALocate
exosome RLID00047563 Link to RNALocate

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).