Basic information:

Untranslated mRNA: Sponge mRNA

Related IDs	cncRNA ID	CNC_M_001927
	Name	Angpt2
	Gene ID	11601
Location	Coordinate(Strand)	8:18690263-18741562(-)
Locus Sequence
Organism	Mus musculus

Evidence support:

  

In vivo/vitro assay	In vitro assay
Low-throughput method	Transfection assay;Western blotting;qRT-PCR;Luciferase assay;Intraocular injection of miRNA mimic
High-throughput method	/
Tissue/Cell	RF/6A cell
Description of experimental evidence	The mRNA was detected by transfection assay, western blotting, qRT-PCR, luciferase assay, intraocular injection of miRNA mimic in RF/6A cell, which can induce hypoxia-induced microvascular dysfunction by binding miR-351, acting as a decoy for Vegf-targeting microRNAs.

Orthologues:

  

Human	ENSG00000091879
Chimpanzee	ENSPTRG00000019947
Drosophila	/
Zebrafish	ENSDARG00000014946

References:

  

PMID	25172656
Description	Bioinformatics prediction and 3'-UTR luciferase assay revealed that Ang-2 and VEGF is commonly targeted by miR-351. miRNA-dependent crosstalk between Ang-2 and VEGF plays a role in hypoxia-induced microvascular response.

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).