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Detail Information


Basic information:


Untranslated mRNA: Sponge mRNA

Related IDs cncRNA ID CNC_M_001440
Name AFF1
Gene ID 4299
Location Coordinate(Strand) 4:86935002-87141054(+)
Locus Sequence
Organism Homo sapiens

Evidence support:

  
In vivo/vitro assay In vitro assay and in vivo assay (Mouse)
Low-throughput method Transfection assay;Western blotting;qRT-PCR;Luciferase assay;siRNA;Proliferation assay
High-throughput method /
Tissue/Cell A375 cell;WM35 cell;451Lu cell;WM278 cell
Description of experimental evidence The mRNA was detected by transfection assay, western blotting, qRT-PCR, luciferase assay, siRNA and proliferation assay in A375 cell, WM35 cell, 451Lu cell and WM278 cell, which can act as a decoy for Pten-targeting microRNAs in melanoma

Orthologues:

  
Chimpanzee ENSPTRG00000016255  
Mouse ENSMUSG00000029313  
Drosophila FBgn0041111  
Zebrafish /

References:

  
PMID 22000016
Description We report the discovery of significant enrichment of putative PTEN ceRNAs among genes whose loss accelerates tumorigenesis following sleeping beauty insertional mutagenesis in a mouse model of melanoma.

Related Subcelluar Localization:

  
Subcelluar Localization RLID Link to RNALocate
Nucleus RLID00039477 Link to RNALocate
Cytoplasm RLID00039478 Link to RNALocate
chromatin RLID00080528 Link to RNALocate
cytosol RLID00080529 Link to RNALocate
insoluble cytoplasm RLID00080530 Link to RNALocate
nucleolus RLID00080531 Link to RNALocate
nucleoplasm RLID00080532 Link to RNALocate
nucleus RLID00080533 Link to RNALocate
nucleus RLID00080534 Link to RNALocate
nucleus RLID00080535 Link to RNALocate
exosome RLID00080536 Link to RNALocate

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).