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Detail Information


Basic information:


Untranslated mRNA: Scaffold mRNA

Related IDs cncRNA ID CNC_M_001906
Name vegt
Gene ID 394452
Location Coordinate(Strand) 1:152851701-152863100(-)
Locus Sequence
Organism Xenopus laevis

Evidence support:

  
In vivo/vitro assay In vitro assay
Low-throughput method Molecular beacon assay;RNA in situ hybridization;Cytoskeleton staining
High-throughput method /
Tissue/Cell Oocyte
Description of experimental evidence The mRNA was detected by molecular beacon assay and RNA in situ hybridization in oocyte, which can act as a scaffold in cytoskeleton and interferes with proper formation of the germinal granules and subsequent development of the germline.

Orthologues:

  
Human /
Chimpanzee /
Mouse /
Drosophila /
Zebrafish /

References:

  
PMID 16000384
Description We found that the organization of the cytokeratin filaments but not the actin cytoskeleton depends on the presence of intact VegT mRNA and a noncoding RNA, Xlsirts.These results demonstrate a novel structural role of coding and noncoding RNAs in the organization of the vegetal cortex of Xenopus oocytes.

Related Subcelluar Localization:

  
Subcelluar Localization RLID Link to RNALocate
Vegetal RLID00012305 Link to RNALocate