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Detail Information


Basic information:


Untranslated mRNA: Scaffold mRNA

Related IDs cncRNA ID CNC_M_002003
Name Raf1
Gene ID 110157
Location Coordinate(Strand) 6:115618067-115676635(-)
Locus Sequence
Organism Mus musculus

Evidence support:

  
In vivo/vitro assay In vitro assay
Low-throughput method /
High-throughput method RIP-seq
Tissue/Cell Embryonic stem cell (ES cell)
Description of experimental evidence The mRNA was detected by RIP-seq in ES cell, which can interact with EZH2 in PRC2 complex.

Orthologues:

  
Human ENSG00000132155  
Chimpanzee ENSPTRG00000014635  
Drosophila /
Zebrafish ENSDARG00000096415   ENSDARG00000059406   ENSDARG00000102328  

References:

  
PMID 21172659
Description Here we develop a RIP-seq method to capture the PRC2 transcriptome and identify a genome-wide pool of 9000 PRC2-interacting RNAs in embryonic stem cells. A large number of transcripts occur within imprinted regions, oncogene and tumor suppressor loci, and stem cell-related bivalent domains. We provide evidence for direct RNA-protein interactions, most likely via the Ezh2 subunit. We also identify Gtl2 RNA as a PRC2 cofactor that directs PRC2 to the reciprocally imprinted Dlk1 coding gene. The data were collected from Supplementary tables.

Related Subcelluar Localization:

  
Subcelluar Localization RLID Link to RNALocate
Nucleus RLID00001849 Link to RNALocate

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).