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Detail Information


Basic information:


Untranslated mRNA: Regulatory mRNA

Related IDs cncRNA ID CNC_M_001433
Name TPM3
Gene ID 7170
Location Coordinate(Strand) 1:154155304-154194648(-)
Locus Sequence
Organism Homo sapiens

Evidence support:

  
In vivo/vitro assay In vitro assay
Low-throughput method PKR kinase Assay;In vitro translation assay;Immunoprecipitation
High-throughput method /
Tissue/Cell /
Description of experimental evidence The mRNA was detected by immunoprecipitation, PKR activation assay and in vitro translation assay, which can inhibit translation by activate PKR.

Orthologues:

  
Chimpanzee ENSPTRG00000045090   ENSPTRG00000001375   ENSPTRG00000045640   ENSPTRG00000048529   ENSPTRG00000046928   ENSPTRG00000044997  
Mouse ENSMUSG00000058126  
Drosophila /
Zebrafish ENSDARG00000005162  

References:

  
PMID 8552671
Description In vitro activation of the interferon-induced, double-stranded RNA-dependent protein kinase PKR by RNA from the 3' untranslated regions of human alpha-tropomyosin.

Related Subcelluar Localization:

  
Subcelluar Localization RLID Link to RNALocate
Nucleus RLID00040487 Link to RNALocate
Cytoplasm RLID00040488 Link to RNALocate
chromatin RLID00101714 Link to RNALocate
nucleolus RLID00101715 Link to RNALocate
nucleoplasm RLID00101716 Link to RNALocate
nucleus RLID00101717 Link to RNALocate
nucleus RLID00101718 Link to RNALocate
exosome RLID00101719 Link to RNALocate
Ribosome RLID00020883 Link to RNALocate
Nucleus RLID00020884 Link to RNALocate
Cytoplasm RLID00020885 Link to RNALocate

Related Diseases:

  
OMIM Phenotype Phenotype MIM number Link to OMIM
congenital fiber-type disproportion OMIM:255310 Link to OMIM
Nemaline myopathy 1, autosomal dominant or recessive OMIM:609284 Link to OMIM
CAP myopathy 1 OMIM:609284 Link to OMIM

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).