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Detail Information


Basic information:


Untranslated mRNA: Regulatory mRNA

Related IDs cncRNA ID CNC_M_001436
Name VEGFA
Gene ID 7422
Location Coordinate(Strand) 6:43770184-43786487(+)
Locus Sequence
Organism Homo sapiens

Evidence support:

  
In vivo/vitro assay In vitro assay and in vivo assay (Mouse)
Low-throughput method Mutation assay;TUNEL-staining
High-throughput method /
Tissue/Cell HCT116 cell
Description of experimental evidence The mRNA was detected by mutation assay and TUNEL-staining in HCT116 cell, which harbour anti-apoptotic effect.

Orthologues:

  
Chimpanzee ENSPTRG00000043213  
Mouse ENSMUSG00000023951  
Drosophila /
Zebrafish ENSDARG00000034700   ENSDARG00000103542  

References:

  
PMID 18494554
Description These findings suggest that cancer cells have a survival system that is regulated by vegf mRNA and imply that both vegf mRNA and its protein may synergistically promote the malignancy of tumor cells.

Related Subcelluar Localization:

  
Subcelluar Localization RLID Link to RNALocate
chromatin RLID00102892 Link to RNALocate
insoluble cytoplasm RLID00102893 Link to RNALocate
membrane RLID00102894 Link to RNALocate
nucleolus RLID00102895 Link to RNALocate
nucleoplasm RLID00102896 Link to RNALocate
nucleus RLID00102897 Link to RNALocate
nucleus RLID00102898 Link to RNALocate
nucleus RLID00102899 Link to RNALocate
exosome RLID00102900 Link to RNALocate
Nucleus RLID00021519 Link to RNALocate
Ribosome RLID00021520 Link to RNALocate
Ribosome RLID00021521 Link to RNALocate
Endoplasmic reticulum RLID00021522 Link to RNALocate
Endoplasmic reticulum RLID00021523 Link to RNALocate
Ribosome RLID00021524 Link to RNALocate

Related Diseases:

  
OMIM Phenotype Phenotype MIM number Link to OMIM
Microvascular complications of diabetes 1 OMIM:603933 Link to OMIM

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).