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Detail Information
Basic information:
Untranslated mRNA: Regulatory mRNA
| Related IDs | cncRNA ID | CNC_M_001423 | |
|---|---|---|---|
| Name | PLAGL2 | ||
| Gene ID | 5326 | ||
| Location | Coordinate(Strand) | 20:32192504-32207743(-) | |
| Locus Sequence | |||
| Organism | Homo sapiens | ||
Evidence support:
| In vivo/vitro assay | In vitro assay and in vivo assay (Mouse) | |
|---|---|---|
| Low-throughput method | Transfection assay;qRT-PCR;Cell migration and invasion assay | |
| High-throughput method | / | |
| Tissue/Cell | Colorectal cancer tissue;SW620 cell;HCT116 cell | |
| Description of experimental evidence | The mRNA was detected by transfection assay and cell migration and invasion assay in SW620 cell and HCT116 cell, which can promote the progression of CRC. | |
Orthologues:
| Chimpanzee | ENSPTRG00000013374 |
|---|---|
| Mouse | ENSMUSG00000051413 |
| Drosophila | FBgn0033581 FBgn0001180 |
| Zebrafish | ENSDARG00000076657 ENSDARG00000036855 |
References:
| PMID | 29512763 |
|---|---|
| Description | These results suggested that high expression of PLAGL2 in CRC was associated with CNV, miR-486-5p and HuR expression, whose 3'-UTR may promote colon carcinogenesis and serve as a novel potential biomarker for CRC therapies. |
Related Subcelluar Localization:
| Subcelluar Localization | RLID | Link to RNALocate |
|---|---|---|
| chromatin | RLID00085889 | Link to RNALocate |
| nucleolus | RLID00085890 | Link to RNALocate |
| nucleoplasm | RLID00085891 | Link to RNALocate |
| nucleus | RLID00085892 | Link to RNALocate |
| nucleus | RLID00085893 | Link to RNALocate |
| exosome | RLID00085894 | Link to RNALocate |
| Ribosome | RLID00015159 | Link to RNALocate |
| Cytosol | RLID00015160 | Link to RNALocate |
Related Interactions:
Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).