Go Back

Detail Information


Basic information:


Untranslated mRNA: Regulatory mRNA

Related IDs cncRNA ID CNC_M_001419
Name ndr1
Gene ID 799352
Location Coordinate(Strand) 21:21010786-21013085(+)
Locus Sequence
Organism Danio rerio

Evidence support:

  
In vivo/vitro assay In vitro assay and in vivo assay (Zebrafish)
Low-throughput method RNA in situ hybridization;In vitro translation assay;Mutation assay
High-throughput method /
Tissue/Cell Embryo
Description of experimental evidence The mRNA was detected by mutation assay and in vitro translation in embryo, which can mediate Dorsal activity of maternal squint.

Orthologues:

  
Human /
Chimpanzee /
Mouse /
Drosophila /

References:

  
PMID 22721777
Description Here, we show that sqt RNA may function independently of Sqt protein in dorsal specification. sqt insertion mutants express localized maternal sqt RNA. Overexpression of mutant/non-coding sqt RNA and, particularly, the sqt 3'UTR, leads to ectopic nuclear Beta-catenin accumulation and expands dorsal gene expression.