Detail

Basic information:

Untranslated mRNA: Regulatory mRNA

Related IDs	cncRNA ID	CNC_M_002054
	Name	IoEve
	Gene ID	/
Organism	Ilyanassa obsoleta

Evidence support:

In vivo/vitro assay	In vivo assay (Ilyanassa obsoleta)
Low-throughput method	RNA in situ hybridization;Immunohistochemistry
High-throughput method	/
Tissue/Cell	/
Description of experimental evidence	The mRNA was detected by RNA in situ hybridization and immunohistochemistry on Ilyanassa obsoleta, which localized to specific subsets of cells during embryonic cleavage.

Orthologues:

Human	/
Chimpanzee	/
Mouse	/
Drosophila	/
Zebrafish	/

References:

PMID	12478296
Description	We followed IoEve, IoDpp and IoTld in later cleavages stages. All three were associated with centrosomes, and all three were sorted during cell division. By the 24-cell stage, IoEve became localized to three particular cells that give rise to the ciliated band of the larvae. IoDpp was segregated into the second and third quartet micromeres, but decayed in the second quartet cells after the production of the third quartet, resulting in a specific localization in the third quartet cells, as well as in one macromere. IoTld was loaded onto centrosomes in all of the first quartet cells, but persisted only in the dorsal cell 1d1. These events produce a complex pattern of mRNA localization, in which different messages distinguish groups of cells with the same birth order rank and similar developmental potentials.

PMID

12478296

Description

We followed IoEve, IoDpp and IoTld in later cleavages stages. All three were associated with centrosomes, and all three were sorted during cell division. By the 24-cell stage, IoEve became localized to three particular cells that give rise to the ciliated band of the larvae. IoDpp was segregated into the second and third quartet micromeres, but decayed in the second quartet cells after the production of the third quartet, resulting in a specific localization in the third quartet cells, as well as in one macromere. IoTld was loaded onto centrosomes in all of the first quartet cells, but persisted only in the dorsal cell 1d1. These events produce a complex pattern of mRNA localization, in which different messages distinguish groups of cells with the same birth order rank and similar developmental potentials.