Basic information:

Untranslated mRNA: Regulatory mRNA

Related IDs	cncRNA ID	CNC_M_001416
	Name	IFNG
	Gene ID	3458
Location	Coordinate(Strand)	12:68154768-68159740(-)
Locus Sequence
Organism	Homo sapiens

Evidence support:

  

In vivo/vitro assay	In vitro assay
Low-throughput method	Mutation assay;In vitro translation assay
High-throughput method	/
Tissue/Cell	Reticulocyte;BHK-21 cell
Description of experimental evidence	The mRNA was detected by mutation assay and in vitro translation in BHK-21 cell, which can inhibit translation by activate PKR.

Orthologues:

  

Chimpanzee	ENSPTRG00000005193
Mouse	ENSMUSG00000055170
Drosophila	/
Zebrafish	ENSDARG00000024211   ENSDARG00000045671

References:

  

PMID	11832212
Description	Human interferon-gamma mRNA autoregulates its translation through a pseudoknot that activates the interferon-inducible protein kinase PKR.

Related Subcelluar Localization:

  

Subcelluar Localization	RLID	Link to RNALocate
exosome	RLID00076717	Link to RNALocate

Related Diseases:

  

OMIM Phenotype	Phenotype MIM number	Link to OMIM
AIDS, rapid progression to	OMIM:609423	Link to OMIM
Hepatitis C virus, response to therapy of	OMIM:609532	Link to OMIM
Tuberculosis, protection against	OMIM:607948	Link to OMIM
Aplastic anemia	OMIM:609135	Link to OMIM
TSC2 angiomyolipomas, renal, modifier of	OMIM:613254	Link to OMIM

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).