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Detail Information
Basic information:
Untranslated mRNA: Regulatory mRNA
| Related IDs | cncRNA ID | CNC_M_001415 | |
|---|---|---|---|
| Name | HIST1H1C | ||
| Gene ID | 3006 | ||
| Location | Coordinate(Strand) | 6:26055740-26056470(-) | |
| Locus Sequence | |||
| Organism | Homo sapiens | ||
Evidence support:
| In vivo/vitro assay | In vitro assay | |
|---|---|---|
| Low-throughput method | Mutation assay | |
| High-throughput method | formaldehyde cross-linking followed by RNA antisense purification and RNA sequencing (RAP-RNA[FA]RNA-seq) | |
| Tissue/Cell | Hela cell;VA13 cell;HT1080 cell | |
| Description of experimental evidence | The mRNA was detected by RAP-RNA[FA]RNA-seq in Hela and VA 13 cell, which can interact with the telomerase RNA to regulate telomere length homeostasis. | |
Orthologues:
| Chimpanzee | ENSPTRG00000017804 |
|---|---|
| Mouse | ENSMUSG00000036181 |
| Drosophila | / |
| Zebrafish | / |
References:
| PMID | 30355447 |
|---|---|
| Description | Our data provide important insights into a surprisingly complex hTR-RNA interaction network and define an unexpected non-coding RNA role for HIST1H1C in regulating telomere length homeostasis, thus offering a glimpse into the mostly uncharted, vast space of non-canonical messenger RNA functions. |
Related Subcelluar Localization:
| Subcelluar Localization | RLID | Link to RNALocate |
|---|---|---|
| cytosol | RLID00075044 | Link to RNALocate |
| insoluble cytoplasm | RLID00075045 | Link to RNALocate |
| nucleus | RLID00075046 | Link to RNALocate |
| nucleus | RLID00075047 | Link to RNALocate |
| exosome | RLID00075048 | Link to RNALocate |
| Cytosol | RLID00009985 | Link to RNALocate |
| Ribosome | RLID00009986 | Link to RNALocate |
Related Interactions:
Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).