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Detail Information
Basic information:
Untranslated mRNA: Regulatory mRNA
| Related IDs | cncRNA ID | CNC_M_001414 | |
|---|---|---|---|
| Name | HIC | ||
| Gene ID | 29969 | ||
| Location | Coordinate(Strand) | 7:114922154-115019202(+) | |
| Locus Sequence | |||
| Organism | Homo sapiens | ||
Evidence support:
| In vivo/vitro assay | In vitro assay | |
|---|---|---|
| Low-throughput method | Immunoprecipitation;Western blotting | |
| High-throughput method | / | |
| Tissue/Cell | Hela cell | |
| Description of experimental evidence | The mRNA was detected by displacing 7SK RNA, immunoprecipitation and western blotting in Hela cell, which can activate transcription elongation. | |
Orthologues:
| Chimpanzee | ENSPTRG00000019609 |
|---|---|
| Mouse | ENSMUSG00000041390 |
| Drosophila | / |
| Zebrafish | ENSDARG00000074223 |
References:
| PMID | 17925858 |
|---|---|
| Description | We report that P-TEFb-dependent transcription from the HIV promoter can be stimulated by the mRNA encoding HIC, the human I-mfa domain-containing protein. The 3'-untranslated region of HIC mRNA is necessary and sufficient for this action. |