Go Back

Detail Information


Basic information:


Translated ncRNA: circRNA

Related IDs cncRNA ID CNC_N_000028
Name circPPP1R12A
Gene ID ENSG00000058272
Location Coordinate(Strand) 12:79773563-79935460(-)
Locus Sequence
Organism Homo sapiens

Peptide information:

  
Peptide GRLRHVNCLSPGVQD
Peptide length 15

Evidence support:

  
In vivo/vitro assay In vitro assay and in vivo assay (Mouse)
Low-throughput method Western blotting;Liquid chromatography-tandem mass spectrometry (LC-MS/MS);SDS-PAGE
High-throughput method /
Tissue/Cell Colorectal tumor sample
Description of experimental evidence The peptide was detected by SDS-PAGE, western blotting and LC/MS in colorectal cell, which can promote tumor pathogenesis and metastasis of colon cancer via Hippo-YAP signaling.

Orthologues:

  
Chimpanzee ENSPTRG00000005252  
Mouse ENSMUSG00000019907  
Drosophila /
Zebrafish ENSDARG00000010784  

References:

  
PMID 30925892
Description A novel protein encoded by a circular RNA circPPP1R12A promotes tumor pathogenesis and metastasis of colon cancer via hippo-YAP signaling.

Related Diseases:

  
Disease MNDR ID Link to MNDR
Colon cancer MNDR-E-CIRC-1404 Link to MNDR