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Detail Information


Basic information:


Translated ncRNA: circRNA

Related IDs cncRNA ID CNC_N_000027
Name hsa_circ_28626
Gene ID ENSG00000146414
Location Coordinate(Strand) 6:145864245-145964423(-)
Locus Sequence
Organism Homo sapiens

Peptide information:

  
Peptide MKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATIEERMQAMLKTAERRAAILQKWKLWSEL
Peptide length 146

Evidence support:

  
In vivo/vitro assay In vitro assay
Low-throughput method Immunoprecipitation;Liquid chromatography-tandem mass spectrometry (LC-MS/MS)
High-throughput method /
Tissue/Cell 293T cell;U251 cell;U373 cell;Glioblastoma cell;Brain
Description of experimental evidence The peptide was detected by immunoprecipitation in 293T cell, and the function of peptide was validated in U251 cell, U373 cell, glioblastoma cell and normal brain.

Orthologues:

  
Chimpanzee ENSPTRG00000018683  
Mouse ENSMUSG00000090112  
Drosophila /
Zebrafish /

References:

  
PMID 29343848
Description In this study, we show that a circRNA containing an open reading frame (ORF) driven by the internal ribosome entry site (IRES) can translate a functional protein. The circular form of the SNF2 histone linker PHD RING helicase (SHPRH) gene encodes a novel protein that we termed SHPRH-146aa.