Detail

Basic information:

Translated ncRNA: circRNA

Related IDs	cncRNA ID	CNC_N_001815
	Name	circ-Ncx1
	Gene ID	ENSRNOG00000008479
Location	Coordinate(Strand)	6:4258991-4520604(-)
Locus Sequence
Organism	Rattus norvegicus

Evidence support:

In vivo/vitro assay	In vitro assay
Low-throughput method	Western blotting;Oligonucleotide affinity chromatography;IPCR;RT-PCR
High-throughput method	/
Tissue/Cell	Kidney
Description of experimental evidence	The peptide was detected by western blotting in kidney.

Orthologues:

Human	ENSG00000183023
Chimpanzee	ENSPTRG00000011861
Mouse	ENSMUSG00000054640
Drosophila	/
Zebrafish	ENSDARG00000043406

References:

PMID	10075718
Description	In the present report we demonstrate that the 1.8-kb message, which has a tissue and subcellular distribution matching that of full-length NCX1 but is not polyadenylated, corresponds to a perfectly circularized exon 2 species. The circular transcript contained the normal NCX1 start codon, a new stop codon introduced as a consequence of circularization, and encoded a protein corresponding to the NH2-terminal portion of NCX1, terminating just after amino acid 600 in the cytoplasmic loop.

PMID

10075718

Description

In the present report we demonstrate that the 1.8-kb message, which has a tissue and subcellular distribution matching that of full-length NCX1 but is not polyadenylated, corresponds to a perfectly circularized exon 2 species. The circular transcript contained the normal NCX1 start codon, a new stop codon introduced as a consequence of circularization, and encoded a protein corresponding to the NH2-terminal portion of NCX1, terminating just after amino acid 600 in the cytoplasmic loop.