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Detail Information


Basic information:


Translated ncRNA: lncRNA

Related IDs cncRNA ID CNC_N_001802
Name dilp8
Gene ID 39909
Location Coordinate(Strand) 3L:17029812-17032080(-)
Notes It has been re-annotated as protein coding gene now
Locus Sequence
Organism Drosophila melanogaster

Evidence support:

  
In vivo/vitro assay In vitro assay and in vivo assay (Larva;Adult fly)
Low-throughput method Immunoprecipitation;Western blotting
High-throughput method /
Tissue/Cell S2R+ cell;Larva
Description of experimental evidence The peptide was detected by immunoprecipitation and western blotting in S2R+ cell, which can delay metamorphosis without affecting tissue integrity.

Orthologues:

  
Human /
Chimpanzee /
Mouse /
Zebrafish /

References:

  
PMID 22556251
Description dilp8 is highly induced in conditions where growth impairment produces a developmental delay. dilp8 encodes a peptide for which expression and secretion are sufficient to delay metamorphosis without affecting tissue integrity.